"Kelly, happy birthday! 50—wow!" Oprah started off her special minute-long message that was played on Live with Kelly and Ryan. "I am sending you the best of wishes as you come into—I'm telling you—the most incredible decade of your life." "I am sending you the best of wishes as you come into—I'm telling you—the most incredible decade of your life." ALSO: Looking back at Ripa through the years.
TOPICS: Kelly Ripa, ABC, Live with Kelly and Ryan, Oprah Winfrey, Daytime TV